Application of Ionic Liquids in Pot-in-Pot Reactions

Application of Ionic Liquids in Pot-in-Pot Reactions.

Pot-in-pot reactions are designed such that two reaction media (solvents, catalysts and reagents) are isolated from each other by a polymeric membrane similar to matryoshka dolls (Russian nesting dolls). The first reaction is allowed to progress to completion before triggering the second reaction in which all necessary solvents, reactants, or catalysts are placed except for the starting reagent...

Application of Green Chemistry in Synthesis of Functionalized Thiopyran viaOne-pot Multicomponent Reactions in Water

An efficient synthesis of 2H-thiopyran-3,4-dicarboxylate derivatives via one-pot reactions between acetylenic esters, arylisothiocyanates and enaminones in water is described.The advantages of this work were: (1) the reaction was performed under neutral and more important in water as the solvent. (2) No catalyst was required for this reaction. (3) The simplicity of the present procedure made it...

One-pot synthesis of highly regioselective β-azido alcohols catalyzed by Brønsted acidic ionic liquids

In this protocol, 3-(2-carboxybenzoyl)-1-methyl-1H-imidazol-3-ium chloride [Cbmim]Cl and sulfonic acid functionalized pyridinium chloride [pyridine-SO3H]Cl as a new, reusable, and green Brønsted acidic ionic liquid (BAIL) catalyst were synthesized and successfully used for the one-pot ring opening of epoxide with sodium azide (NaN3) in water at room temperature. Epoxides under ring-opening easi...

Catalytic reactions in ionic liquids.

The chemical industry is under considerable pressure to replace many of the volatile organic compounds (VOCs) that are currently used as solvents in organic synthesis. The toxic and/or hazardous properties of many solvents, notably chlorinated hydrocarbons, combined with serious environmental issues, such as atmospheric emissions and contamination of aqueous effluents is making their use prohib...

Pot-in-pot reactions: a simple and green approach to efficient organic synthesis